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Awọn ọja

6-Methyluracil 2,4-Dihydroxy-6-methylpyrimidine

Apejuwe kukuru:


  • Orukọ Kemikali:6-Methyluracil 2,4-Dihydroxy-6-methylpyrimidine
  • CAS No.:626-48-2
  • CAS ti bajẹ:15985-99-6,78334-35-7,78334-35-7
  • Fọọmu Molecular:C5H6N2O2
  • Iṣiro Awọn Atomu:5 awọn ọta erogba, awọn ọta hydrogen 6, awọn ọta Nitrogen 2, awọn ọta atẹgun 2,
  • Ìwúwo Molikula:126.115
  • Koodu Hs.:29335995
  • Nọmba Agbegbe European (EC):210-949-4
  • Nọmba NSC:9456
  • UNII:5O052W0G6I
  • ID nkan elo DSSTox:DTXSID8052308
  • Nọmba Nikkaji:J39.643E
  • Wikidata:Q4161980
  • Metabolomics Workbench ID:87091
  • ChEMBL ID:CHEMBL1650614
  • Mol faili: 626-48-2.mol
  • Alaye ọja

    ọja Tags

    ọja (1)

    Awọn itumọ ọrọ: 6-methyluracil; 6-methyluracil, 14C-aami; AWD 23-15; AWD-23-15; methacil; methyluracil; pseudothymine

    Ohun-ini Kemikali ti 6-Methyluracil

    ● Irisi/Awọ:funfun si pa-funfun kristali ti o lagbara
    ● Ipa oru: 1.16E-07mmHg ni 25 ° C
    ● Oju Iyọ: 318 °C (oṣu kejila) (tan.)
    ● Atọka Refractive: 1.489
    ● Ojumi Sise: 420.4 °C ni 760 mmHg
    ● PKA: pK1:9.52 (25°C)
    ● Aaye Flash: 208 °C
    ● PSA: 65.72000
    ● iwuwo: 1.226 g / cm3
    ● LogP: -0.62840

    ● Iwọn otutu Ibi ipamọ.:Aaye inert,Iwọn otutu yara
    ● Solubility.:DMSO (Diẹ), kẹmika (Diẹ, Kikan, Sonicated)
    ● Omi Solubility.:7 g/L (22ºC)
    ● XLogP3: -0.8
    ● Awọn oluranlọwọ Idena Hydrogen: 2
    ● Iwọn Apejọ Idena Hydrogen: 2
    ● Iwọn iwe adehun Yiyipo: 0
    ● Iwọn gangan: 126.042927438
    ● Iwọn Atomu Eru:9
    ● Àkópọ̀:195

    Mimo / Didara

    99% * data lati awọn olupese aise

    6-Methyluracil * data lati awọn olupese reagent

    Alaye ailewu

    ● Pitogram(s):ọja (2)Xn
    ● Awọn koodu ewu: Xn
    ● Gbólóhùn: 62-63
    ● Awọn Gbólóhùn Aabo: 36/37/39-45-36/37

    Wulo

    ● SILES Canonical: CC1=CC(=O)NC(=O)N1
    ● Nlo: 6-Methyluracil (cas # 626-48-2) jẹ ohun elo ti o wulo ninu iṣelọpọ ti ara.O jẹ itọsẹ pyrimidine ati paati awọn acids nucleic.Thymine, pẹlu adenine, cytosine, ati guanine, jẹ ọkan ninu awọn nucleobases mẹrin ti a rii ni DNA.Thymine ṣe ipa pataki ninu DNA nipa sisopọ pẹlu adenine nipasẹ isunmọ hydrogen, ti o ṣe ọkan ninu awọn orisii ipilẹ ti o ṣe agbekalẹ helix meji.Ni pato, thymine ṣe awọn asopọ hydrogen meji pẹlu adenine ninu DNA.Ni RNA, uracil rọpo thymine ati pe o tun ṣe awọn orisii ipilẹ pẹlu adenine.Thymine jẹ iduro fun gbigbe alaye jiini laarin moleku DNA.O ṣe bi apẹrẹ fun iṣelọpọ ti awọn ọlọjẹ ati pe o ṣe ipa pataki ninu gbigbe awọn ẹda jiini lati iran kan si ekeji.Yato si ipa rẹ ninu DNA ati RNA, thymine tun jẹ ibi-afẹde pataki ninu awọn oogun anticancer.Diẹ ninu awọn aṣoju chemotherapeutic fojusi awọn enzymu ti o ni iduro fun sisọpọ thymine, nitorinaa dẹkun idagba awọn sẹẹli alakan.Thymine wa ni iṣowo ati lilo pupọ ni iwadii ijinle sayensi, awọn ohun elo iṣoogun, ati ile-iṣẹ oogun.Nigbati o ba n ṣetọju thymine, o ṣe pataki lati tẹle awọn ilana aabo ile-iyẹwu to dara, pẹlu wọ ohun elo aabo ti o yẹ ati ṣiṣẹ ni agbegbe ti o ni afẹfẹ daradara.Ni afikun, thymine yẹ ki o wa ni ipamọ ni aaye gbigbẹ ati itura lati ṣe idiwọ ibajẹ ati ṣetọju iduroṣinṣin rẹ.


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