Awọn ọja
4-Hydroxy-D (-) -2-phenylglycine
Synonyms: (R, S) -3HPG; 4-hydroxyphenylglycine; 4-hydroxyphenylglycine hydrobromide, (+-)-isomer; 4-hydroxyphenylglycine hydrochloride, (R) -isomer; 4-hydroxyphenylglycine perchlorate, (+-) -isomer; 4 -hydroxyphenylglycine, (+-)-isomer; 4-hydroxyphenylglycine, (R) -isomer; 4-hydroxyphenylglycine, (S) -isomer; 4-hydroxyphenylglycine, 2,4-dimethylbenzenesulfonate, (+-) - isomer; 4-hydroxyphenylglycine , 2,4-dimethylbenzenesulfonate, (R) -isomer; 4-hydroxyphenylglycine, 4-methylbenzenesulfonate, (+-) -isomer; 4-hydroxyphenylglycine, 4-methylbenzenesulfonate, (S) -isomer; 4-hydroxyphenylglycine, monosodium iyọ; -hydroxyphenylglycine, iyọ monosodium, (R) -isomer; Dp-hydroxyphenylglycine; L-4-hydroxyphenylglycine; oxfenicine; p-hydroxyphenylglycine; UK 25842; UK-25842
Ohun-ini Kemikali ti D (-)-4-Hydroxyphenylglycine
● Irisi / Awọ: pa-funfun lulú
● Ipa oru: 0.000272mmHg ni 25 ° C
● Oju Iyọ: 240 °C (oṣu kejila) (tan.)
● Atọka Refractive: -158 ° (C=1, 1mol/L HCl)
● Ojumi Sise: 365.8 °C ni 760 mmHg
● PKA: 2.15 ± 0.10 (Asọtẹlẹ)
● Aaye Filasi: 175 °C
● PSA: 83.55000
● iwuwo: 1.396 g / cm3
● LogP: 1.17690
● Ibi ipamọ otutu: Tọju ni isalẹ +30°C.
● Solubility.:5g/l
● Omi Solubility.:5 g/L (20ºC)
● XLogP3: -2.1
● Awọn olufowosi iwe adehun Hydrogen: 3
● Iwọn Gbigba Idena Hydrogen: 4
● Iwọn Idena Yiyi: 2
● Ibi ti o daju: 167.058243149
● Iwọn Atomu Eru:12
● Àkópọ̀:164
Mimo / Didara
99% * data lati awọn olupese aise
4-Hydroxy-D-(-)-2-phenylglycine * data lati ọdọ awọn olupese reagent
Alaye ailewu
● Pitogram(s):
Xi
● Awọn koodu ewu: Xi
● Awọn Gbólóhùn: 36/37/38
● Awọn Gbólóhùn Aabo: 26-36-24/25
Awọn faili MSDS
Wulo
● SILES Canonical: C1=CC(=CC=C1C(C(=O)O)N)O
● SILES Isomeric: C1=CC(=CC=C1[C@H](C(=O)O)N)O
● Nlo: 4-Hydroxy-D-(-)-2-phenylglycine jẹ agbo-ara ti a lo fun igbaradi sintetiki ti awọn egboogi β-lactam.4-Hydroxy-D- (-) 2-phenylglycine (Cefadroxil EP Impurity A (Amoxicillin EP Impurity A)) jẹ ohun elo ti a lo ni pataki fun igbaradi sintetiki ti awọn egboogi β-lactam.
4-Hydroxy-D-phenylglycine, ti a tun mọ ni 4-hydroxy-D-phenylglycine tabi 4-HDPG, jẹ iṣiro kemikali pẹlu ilana molikula C8H9NO3.O jẹ itọsẹ amino acid ati pe o jẹ ti ẹka ti phenylglycines.4-Hydroxy-D-phenylglycine ni akọkọ ti a lo bi ohun amorindun ni iṣelọpọ ti awọn agbo ogun elegbogi.O jẹ ohun elo aise ni iṣelọpọ ti awọn oogun apakokoro kan, gẹgẹbi cefadroxil ati cephradine.Awọn egboogi wọnyi jẹ ti kilasi cephalosporin ati pe a lo lati ṣe itọju awọn akoran kokoro-arun.Ni afikun si ipa rẹ bi iṣaju ni iṣelọpọ ti oogun, 4-Hydroxy-D-phenylglycine ti tun ṣe iwadi fun awọn ohun-ini itọju ailera ti o pọju.Iwadi ṣe imọran pe o le ni awọn ẹda-ara ati awọn ipa-ipalara-iredodo, eyi ti o le jẹ ki o wulo ni idagbasoke awọn oogun titun fun awọn ipo iṣoogun ti o yatọ.Iwoye, 4-Hydroxy-D-phenylglycine jẹ kemikali kemikali ti o ni awọn ohun elo pataki ni iṣelọpọ oogun ati agbara ti o pọju. mba ipawo.Ipa rẹ gẹgẹbi ohun amorindun ile ni iṣelọpọ awọn oogun aporo ṣe afihan pataki rẹ ni ile-iṣẹ oogun.
