Awọn ọja
2,4-Diamino-6-hydroxypyrimidine
Awọn ohun-ini Kemikali Hydroxypyrimidine
| Ojuami yo | 285-286 °C (oṣu kejila) (tan.) |
| Oju omi farabale | 234.22°C (iṣiro ti o ni inira) |
| iwuwo | 1.3659 (iṣiro ti o ni inira) |
| refractive atọka | 1.7990 (iṣiro) |
| iwọn otutu ipamọ. | Tọju ni aaye dudu, Afẹfẹ Inert, otutu yara |
| solubility | DMSO (Diẹ), kẹmika (Diẹ) |
| pka | 10.61± 0.50 (Asọtẹlẹ) |
| fọọmu | Fine Crystalline Powder |
| awọ | Funfun si ipara |
| Ni imọlara | Imọlẹ Imọlẹ |
| Merck | 14.2981 |
| BRN | 125006 |
| InChiKey | SWELIMKTDYHAOY-UHFFFAOYSA-N |
| CAS DataBase Reference | 56-06-4 (Itọkasi DataBase CAS) |
| NIST Kemistri itọkasi | 4 (1H) -pyrimidinone, 2,6-diamino- (56-06-4) |
| Eto Iforukọsilẹ nkan EPA | 2,6-Diamino-4 (1H) -pyrimidinone (56-06-4) |
Hydroxypyrimidine Ọja Apejuwe
2,4-Diamino-6-hydroxypyrimidine jẹ iṣiro kemikali kan pẹlu ilana molikula C4H6N4O.O jẹ agbo-ara Organic ti o jẹ ti idile pyrimidine.Apapo naa ni eto oruka pyrimidine, awọn ẹgbẹ amino meji (NH2) ti sopọ ni ipo 2 ati ipo 4, ati pe ẹgbẹ hydroxyl (OH) ti sopọ ni ipo 6.Ilana kemikali le ṣe afihan bi:Amonia ||H--C--C--C--N--C--C--NH2 ||oh 2,4-Diamino-6-hydroxypyrimidine ni orisirisi awọn ohun elo ni ile-iṣẹ oogun.O jẹ agbedemeji pataki ni iṣelọpọ ti ọpọlọpọ awọn oogun, pẹlu antiviral ati awọn oogun antitumor.O tun lo lati ṣe agbejade ọpọlọpọ awọn afọwọṣe nucleotide ti a lo ninu iwadii oogun.
Ni afikun si awọn ohun elo elegbogi, 2,4-diamino-6-hydroxypyrimidine tun lo bi eroja ninu awọn agrochemicals.O jẹ eroja pataki ninu iṣelọpọ ti awọn olutọsọna idagbasoke ọgbin ati awọn fungicides.O ṣe pataki pupọ lati tẹle ilana aabo to dara nigba lilo 2,4-diamino-6-hydroxypyrimidine.Niwọn igba ti o ti pin si bi irritant kemikali, o yẹ ki o ṣe itọju pẹlu itọju ati pe ohun elo aabo ti ara ẹni yẹ ki o wọ lati yago fun olubasọrọ taara.
Ni akojọpọ, 2,4-diamino-6-hydroxypyrimidine jẹ agbo-ara Organic pẹlu awọn ohun elo ni awọn ile elegbogi ati awọn aaye ogbin.Ilana kemikali rẹ jẹ ki o wulo bi agbedemeji ninu iṣelọpọ ti awọn oogun ati awọn olutọsọna idagbasoke ọgbin.
Alaye Aabo
| Awọn koodu ewu | Xi |
| Awọn Gbólóhùn Ewu | 36/37/38 |
| Awọn Gbólóhùn Aabo | 22-24/25-36-26 |
| WGK Germany | 3 |
| Akọsilẹ ewu | Irritant |
| TSCA | Bẹẹni |
| HS koodu | 29335995 |
Lilo Hydroxypyrimidine Ati Akopọ
| Apejuwe | 2,4-Diamino-6-hydroxypyrimidine (DAHP) jẹ yiyan, oludena kan pato ti GTP cyclohydrolase I, igbesẹ idiwọn oṣuwọn fun iṣelọpọ de novo pterin.Ninu awọn sẹẹli HUVEC, IC50fun idinamọ ti BH4biosynthesis jẹ nipa 0.3 mM.A le lo DAHP lati ṣe idiwọ iṣelọpọ KO ni imunadoko ni awọn iru sẹẹli pupọ. |
| Kemikali Properties | White Ri to |
| Nlo | 2,4-Diamino-6-hydroxypyrimidine (DAHP) jẹ yiyan, oludena kan pato ti GTP cyclohydrolase I, igbesẹ idiwọn oṣuwọn fun iṣelọpọ de novo pterin.Ninu awọn sẹẹli HUVEC, IC50 fun idinamọ ti biosynthesis BH4 jẹ nipa 0.3 mM.A le lo DAHP lati ṣe idiwọ iṣelọpọ KO ni imunadoko ni awọn oriṣi sẹẹli pupọ.[Cayman Chemical] |
| Nlo | O duro ni ibẹrẹ ti kasikedi-catalyzed henensiamu ti o bẹrẹ pẹlu carbohydrate-erogba meje yii o si pari pẹlu awọn amino acids phenylalanine ti oorun didun, tyrosine, ati tryptophan. |
| Nlo | 2,4-Diamino-6-hydroxypyrimidine (cas # 56-06-4) jẹ ohun elo ti o wulo ninu iṣelọpọ Organic. |
| Awọn ọna ìwẹnumọ | O recrystallises lati H2O.[Beilstein 25 III/IV 3642.] |
