● Irisi/Awọ:funfun to lagbara
● Ipa oru: 0.00232mmHg ni 25 ° C
● Oju Iyọ: 285-286 °C (oṣu kejila) (tan.)
● Atọka Refractive: 1.7990 (iṣiro)
● Oju-ọna Sise: 288.5 °C ni 760 mmHg
● PKA: 10.61 ± 0.50 (Asọtẹlẹ)
● Filaṣi Point: 128.3 °C
● PSA: 98.05000
● iwuwo: 1.84 g / cm3
● LogP: 0.50900
● Iwọn otutu Ibi ipamọ: Yọọ kuro ni +4°C
● Sensitive.: Imọye Imọlẹ
● Solubility.:DMSO (Diẹ), Methanol (Diẹ)
99% * data lati awọn olupese aise
2,4-Diamino-6-hydroxypyrimidine *data lati ọdọ awọn olupese reagent
● Pitogram(s):Xi
● Awọn koodu ewu: Xi
● Awọn Gbólóhùn: 36/37/38
● Awọn Gbólóhùn Aabo: 22-24 / 25-36-26
● Apejuwe: 2,4-Diamino-6-hydroxypyrimidine (DAHP) jẹ yiyan, oludaniloju kan pato ti GTP cyclohydrolase I, igbesẹ ti o ni idiwọn fun de novo pterin synthesis.Ninu awọn sẹẹli HUVEC, IC50 fun idinamọ ti biosynthesis BH4 jẹ nipa 0.3 mM.A le lo DAHP lati ṣe idiwọ iṣelọpọ KO ni imunadoko ni awọn iru sẹẹli pupọ.
● Nlo: 2,4-Diamino-6-hydroxypyrimidine (DAHP) jẹ yiyan, oludena kan pato ti GTP cyclohydrolase I, igbesẹ idinku oṣuwọn fun iṣelọpọ de novo pterin.Ninu awọn sẹẹli HUVEC, IC50 fun idinamọ ti biosynthesis BH4 jẹ nipa 0.3 mM.A le lo DAHP lati ṣe idiwọ iṣelọpọ KO ni imunadoko ni awọn oriṣi sẹẹli pupọ.[Cayman Chemical] O duro ni ibẹrẹ ti kasikedi-catalyzed henensiamu ti o bẹrẹ pẹlu carbohydrate carbon meje ti o pari pẹlu amino acids phenylalanine, tyrosine, ati tryptophan ti oorun didun. 2,4-Diamino-6-hydroxypyrimidine (cas # 56-06-4) jẹ ohun elo ti o wulo ninu iṣelọpọ Organic.
2,4-Diamino-6-hydroxypyrimidine jẹ iṣiro kemikali kan pẹlu ilana molikula C4H6N4O.O ti wa ni commonly lo bi ohun agbedemeji ninu awọn kolaginni ti awọn orisirisi agbo ogun, pẹlu elegbogi oloro ati dyes.The yellow ni o ni a pyrimidine oruka be wa ninu ti meji amino awọn ẹgbẹ (NH2) ati ọkan hydroxyl ẹgbẹ (OH) so si orisirisi erogba awọn ọta.Ilana yii jẹ ki o jẹ ohun elo ile ti o wapọ fun iṣelọpọ ti awọn ohun elo ti o pọju sii.2,4-Diamino-6-hydroxypyrimidine le ṣee gba nipasẹ awọn ọna ti o yatọ si sintetiki, pẹlu ifarahan ti cyanamide pẹlu urea.O ni awọn ohun elo pupọ ni ile-iṣẹ oogun, paapaa ni iṣelọpọ ti awọn oogun anticancer ati awọn oogun aporo.Iwoye, 2,4-Diamino-6-hydroxypyrimidine jẹ ohun elo ti o ṣe pataki ti o rii ohun elo ni orisirisi awọn ohun elo kemikali ati oogun.